文|全球财说 苏杭
qianjinianhaibeipiping“gaodingjia”defangzhiyaoxingyeyiyezhijianbiantianle。
jinri,“3fenqiannengfoushengchanchuyipianasipilin”dehuatishangleresou,qiyinshizaijinqigongbujieguodedishiciquanguoyaopinjizhongcaigouzhong,“asipilinchangrongpian”dezhongbiaodanjiadizhi3.4fenqianyipian,lingbushaorendanxin,rucididecaigoujiashifouhuiyingxiangyaopinzhiliang。
genjudiyicaijingribaodebaodao,asipilindeyuanliaoyaojiagejiaodi,guimohuashengchanxiakeyizuodaozheiyangdedijia,dijiayebingbuyiweizheyaoqiyidinghuitougongjianliao。
shishishang,fangzhiyaozaiquanqiufanweineidoushuyudilirunlvdexingye,quanqiuqianshimingdefangzhiyaoqi,2022niandejinglirunlvjunzai10%zhi16%zhijian。shenzhijiuzaijicaichulufengmangde2021nian,guoneidefangzhiyaohaichangchangbeirenweiyuquanqiushichang“daogua”,ruhegaishan“fangzhiyaogaodingjia”dewenticaishidangshideyiti。
danlingyifangmian,wuyongzhiyideshi,fangzhiyaoxingyeyijicaiweixinhao,yijinruleweilishidai。
创新药已成唯一选择
zuoweijicaidahu,hengruiyiyao(600276. sh)shoudaodeyingxiangsihuyijingzhujianjianruo。
sanjibaoxianshi,2024nianqiansanjidu,hengruiyiyaoyingyeshouru201.89yiyuan,tongbizengzhang18.67%;guishujinglirun46.20yiyuan,tongbizengzhang32.98%。qizhongdisanjidushixianyingyeshouru65.89yiyuan,tongbizengzhang12.72%;guishujinglirun11.88yiyuan,tongbizengzhang18.67%。
lazhangshijianfanweilaikan,hengruiyiyaoxiangshangqushishangshuwending,2006nianyilaizhangqibaochizheliangweishuzengzhang。
zhuanzhechuxianzai2021nian,dangnianhengruiyiyaoyingyeshourutongbixiajiang6.59%,guishujingliruntongbixiajiang28.41%,cinianzaidufenbietongbixiajiang17.87%、13.77%。2023nian,suiranyingshoujinglijunhuifulezengzhang,danjiao2020nianrengyouchaju。
bishixiajiangdeyuanyinshixianeryijiande。hengruiyiyaozai2023niannianbaoji2024nianbannianbaozhongjunbiaoshiqineifangzhiyaoshourulveyouxiahua,“fangzhiyaojicaiduixiaoshourengranzaochengyidingchengdudeyali”。
zaidi1zhidi7pijicaizhong,hengruiyiyaogongzhongxuan22gepinzhong,jiagepingjunjiangfu74.5%,di8zhidi9pijicaizhongyeyouchanpinyi70%yishangdejiangfuzhongbiao。
di10pi“guocai”zhong,hengruiyiyaogongsheji2gepinzhong,nizhongbiao1ge。qizhongnidiyishunweizhongbiaogatesuanpuanzhusheji(15ml:5.654g/15ml:5.6535g*1ping),baojia26.88yuan,jiangfuyue85%。
yinci,hengruideweilaiwuyizaiyuchuangxinyao。
zaozaibenshijichu,gongsidongshizhangsunpiaoyangjiudailinghengruiyiyaokaishileduichuangxinyaodeyanfatansuo。haicengtichu“ercichuangxin”degainian,danyecengbeizhichu“qiaomiaoyongercichuangxingainianlaidaitifangzhiyao,danshizhishangrengshifangzhiyao”。buguo,congme-too、me-betterdecengmian,yenengkanchusunpiaoyangduiyuchuangxinyaozhongyaoxingderenzhichuxing。
puyinguojiyanbaoxianshi,jiezhi2024nian8yue22ri,hengruiyiyaozaiyanchuangxinyaozhuyaolinchuangyanfaguanxiangongyou95xiang。guojizhimingzixunjigoucitelinefabude《2024nianyiyaoyanfanianduhuigu》xianshi,anguanxianguimoji,hengruizaiquanqiuzhiyaogongsizhongpaimingdi8,zaiguoneipaimingdi1。
ranershizhijinri,hengruiyiyaoqueshizhongqueshaozhenzhengyiyishangdequanqiuzhongbangyaopin。
hengruiyiyaozizhuyanfadekangaiyaorenyuanhuapd-1dankelongkangtikaruilizhudankangbenyingdancizhongren,danzi2021nianzaiwanqiganaiyixianzhiliaoshiyingzhengshanghuodelefda(meiguoshipinyaopinjianduguanliju)degueryaorenzhenghoutuijinjiuyizhibushun。
2024nian5yue,fdajiukaruilizhudankanglianheapatini(“shuangai”liaofa)yongyuyixianzhiliaobukeqiechuganxibaoaihuanzhedexinyaoshenqing(nda)fachuwanzhenghuifuhan,yinfdaxujiyuqiyeduishengchanchangdijianchaquexiandewanzhengdafujinxingquanmianpinggu;bingqieyouyubufenguojiadelvxingxianzhi,zaishenchazhouqineiyewufaquanbuwanchenggaixiangmubixudelinchuangjiancha,gailiaofazaimeiguoshenqingyanchihuopi。muqian,hengruiyiyaoyijingzhongxintijiao“shuangai”liaofazaimeishangshishenqing。
erlingwailiangjiaguoneiyaoqidepd-1——baijishenzhou(688235. sh, 06160. hk, bgne.us)detileilizhudankanghejunshishengwu(688180. sh, 01877. hk)deteruipulidankang,xiangjifenbiezaishidaolinaijibiyanaideshiyingzhengshanghuofdapizhun。
huofdapizhunshiyaopinzaiquanqiushangyehuazhiguanzhongyaodeyibu。baijishenzhoudetileilizhudankang2023nian、2024nianshangbanniandexiaoshouefenbieda38.06yiyuan、21.91yiyuan,weiguoneipd-1xiaoshoudiyi。
tongshi,baijishenzhoulingyikuanzizhuyanfadezebutinishishoukuanzaimeiguoshangshideguochankangaixinyao,2023nianquanqiuxiaoshouedadao13yimeiyuan,chengweiguoneishougetuposhiyimeiyuande“zhongbangzhadan”jichuangxinchanpin。
deyiyuzebutinihetileilizhudankangdedafangyicai,baijishenzhoushourukuaisuzengzhang。2024nianqiansanjiduzongyingshoutongbidafuzengzhang48.6%zhi191.36yiyuan,9jiajigouduiqiquannianyingshouyucepingjunzhiyue258yiyuan,dancongyingshoushanglaikan,zhaociqushixiazhuiganshanghengruiyiyaozhirikedai。
dangran,baijishenzhouzaitourufangmianyeshibuyiyuli。2017nianzhi2023nian,baijishenzhouyanfafeiyongcong20.17yiyuanzhuniandafuzengjiazhi128.13yiyuan,2024nianqiansanjidudadao101.66yiyuan。
fanguanhengruiyiyao,cong2011nianyoupilukaishi,qiyanfatouruzengzhangyi“wen”weizhu。2021nianyejixiajiangdetongshi,yanfatouruyelveyoujianshao。2024nianqiansanjidu,hengruiyiyaoyanfafeiyongwei45.49yiyuan,yanfafeiyonglvwei22.53%。
自主出海瞻前顾后
lingyifangmian,baijishenzhounengcongtileilizhudankangzhongshouhuoliangduo,haiyoulaiyuqizizhuchuhaidexingshi。baijishenzhoudeliangdadanpin,zebutini、tileilizhudankangjunweigongsizizhuchuhai。zizhuchuhaiyaomianlindekunnanhefengxianshijudade,danshouyiyebirenheshouquanxingshidougengweikeguan。
duihengruiyiyaolaishuo,cong2018nianzhi2022nian5nianjianneizonggong5bishouquanjiaoyileijijinebuzu5yiyuan,dao2023niandacheng5bizongechaoguo40yimeiyuandelicense-outhezuo,dao2024nian5yuewanchengguoneishoubinewcojiaoyibingdacheng3kuanchanpinyue60yimeiyuanjiaoyi,qichuhaijiaobujiakuai,danxuanzeshanggengjiazhuzhongwen。
license-out,zhiqiyejiangjinxingzaoqiyanfadeyaowuxiangmushouquanjiqitayaoqizuohouqilinchuangyanfaheshangyehua,binganzhaolichengbeimoshihuodegejieduanlinchuangchengguoyijishangyehuahoudeyidingbilixiaoshoufencheng。
newco(newly created company),jijiangguanxiandehaiwaiquanyishouquanjihaiwaichenglidexingongsi,tongshiyinruhaiwaijijin,dajianguojihuaguanlituandui,zhixingongsihaiwaishangshihuobeibinggoucongershixiantuichu。
newcojiaoyibeirenweishizizhuchuhaiyulicense-outdezhongjianxingshi。hengruiyiyaozeshixianqizhongguonewcolangchaodenongchaoer,2024nian5yuehengruiyiyaojiangglp-1chanpinzuheshouquanyuganggangzaimeiguochengli、beienzibenzuoweidagudongdehercules cm newco,inc.,binghuodeshouquanxukefeijigaigongsi19.9%guquan。
shizhijinri,newcoyichengweiguoneichuangxinyaoqichuhaidezhongyaofangshizhiyi,danzheizhongxingshibingbunengjieqianchou,wulunshilicense-outhaishinewco,douxiangdangyufangqilegaichanpinzaishouquandiqudeshichang,yilaizheizhongxingshiyexiangdangyufangqilezaigailingyuchengweiguojihuaqiyedejihui。
haozaihengruiyiyaobingweigubuzifeng。12yue9rixiawu5dian48fen,hengruiyiyaofabugonggao,zhengshixuanbugongsijihuazaijingwaifaxinggufen(hgu)bingzaixiangganglianjiaosuozhubanshangshi。yesuanshiyingzhengleciqian10yuepengbosheduiqinifugangshangshidebaodao。
pengboshebiaoshi,hengruiyiyaoyujirongziguimozhishao20yimeiyuan(yuehe155yigangyuan),huojiangchuangxiaganggushengwuyiyaodemuzijilu。
zaigangshangshihou,hengruiyiyaokeyigengzhijiedijiechuhaiwaiziben。zai2024nian10yuezhaokaidejizhehuishang,xianggangtequzhengfucaizhengsisizhangbiaoshi,jinqiganggujingmairudezijinlaiyuanzhuyaolaizioumeitouzizhe,tamenzhanjingmairujiazhiyue85%。
chuhaifangmian,sunpiaoyangjinribiaoshi:“xianzaiwomenzhuyaoshijiechuanchuhai,zheiyouliangzhongfangshi,yigeshiheguowaidagongsihezuo,shouquanjitamen,zijizaiguowaiganbuledeshiqingjiaojibierenqugan;ershiheguowaidazibenhezuo,tamenzaitouzifangmianyoujingyan。zheiliangzhongxingshiduiyuqiyelaishuonengyouxiaoguibifengxian,tisheng‘chuhai’dexiaolv。”
zhiyuzizhuchuhai,sunpiaoyangrenweimianlindewentibuzhishiguowaigaoanglinchuangfeiyong,haiyouweilaishangyehuadengwenti,buquedingyinsubijiaoduo。
conghengruiyiyaodexuanzelaikan,zhengtihaishituchuyige“qiuwen”,danhuiwangguoqu,hengruiyiyaoxingzhijinri,quelibukaisunpiaoyangyiciyouyicichaoqiandedadanjueding。
闯出来的“医药一哥”
yuhenduoqiyejialeisi,sunpiaoyangyuhengruiyiyaodegushishiyuyigefengyupiaoyaodeguoyingxiaochang。1982nian,gangcongzhongguoyaokedaxuebiyedesunpiaoyangruzhilianyungangzhiyaochang,zuoweiyimingjishuyuankaiqilezaiyiyaoxingyedezhiyeshengya。
1990nian,chengliyijin20niandelianyungangzhiyaochangrengshiyigezhangmianlirunjin8wanyuandezuofangshixiaochang,chanpindanyi、laohua,jingyingjubuweijian。cishi,benyidiaodaolianyungangshiyiyaogongyegongsikejikedanrenfukezhangdesunpiaoyanglinweishouming,tiaoqilechangzhangdezhongdan。
sunpiaoyanghoulaihuiyishuo:“1991nian,wotiantiankancaiwubaobiao,tiantiansuanzhangranggongsihuoxialai。neishihouchanglishengchandeluoxuanmeisu、hongmeisu,yipianmaiyifenqian,leisiyewufagaibianxianzhuang,zongguiyaoxunqiuchulu。”
taweiyaochangzhaodaodechulushikaifaxinyao,zaichanpinjiegoushangzuowenzhang。
jutideqingxingshizhijinriyibukekao,danguangweiliuchuandeshi,sunpiaoyangzaizuanxinyanjiujishudetongshi,zhanxianpoliyimian,shangmakangaizhenjivp16xiangmu,bingkaishishengchangailianghoudejiaonangchanpin,zaibishishichangjihuyipiankongbaideqingkuangxiaqudelejudachenggong,yingliyijutupobaiwan。
cinian,sunpiaoyangzaicilipaizhongyi,nachuyaochangjihuquanbudelirun,chizi120wanyuancongzhongguoyikeyuanyaoyansuonadaolexinkaifadekangaiyaoyihuanlinxianandezhuanliquanjinxinghouxukaifa。zaidangshi,wulunshiduiyaochanghaishisunpiaoyangbenren,zheidousuandeshangyichanghaodu。
xingyundeshi,sunpiaoyangduyingle,bingyoucidiandinglegongsizaikangaiyaoshichangdediwei。
1991nianzhi1996nianqijian,sunpiaoyangdailingquanchangkaifale20duogexinchanpin,qizhong5gebeipingweiguojiajizhongdianchanpin,1996nianyaochangshourupoyi。
1997nian,lianyungangzhiyaochanggaizhiweirujindehengruiyiyao,bingyu2000nianchenggongdengluagushichang。
2003nianzhi2006nian,hengruiyiyaoqidonggugai,sunpiaoyangtongguombo(guanlicengshougou)qudaiguozichengweishijikongzhiren。youyuzheiyishiqigongsigujiashangchuyudiwei,mbochengbenbingbugao。cihou,hengruiyiyaodekangzhongliuyaoxiaoshoulianxu7nianguoneipaimingdiyi。
jinguanshuoshi“kaifaxinyao”,danzaoqidehengruiyiyaoshengchandezhuyaoshifangzhiyao。
houlaizaisunpiaoyangdetuidongxia,hengruiyiyaoyu1997nianhe2000niantouzijin2yiyuanxiangjishelilianyungangheshanghailiangdayanjiuzhongxin,youhaojuzishelilechengdouhemeiguoyanfazhongxinyijiyigelinchuangyixuebu,goujianleyaowubabiaohefenzishaixuan、shengwubiaozhihezhuanhuayixuedengliudachuangxinpingtai,yibubutuidonghengruiyiyaodechuangxinyaoyewu。
keyishuo,hengruiyiyaodejintian,libukaisunpiaoyangpojudepoli。
rujin,fangzhiyaoxingyezaicijinru“jifenqian”shidai。cong1970nianlianyungangzhiyaochangchenglisuanqi,zhijinyiguo“zhitianming”dehengruiyiyao,yiji2020nianchubianzhunbeituixiu、20geyuehouquebudebufuchuliwankuanglandesunpiaoyang,youhaishengjifenchuangyedejiqingni?
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